St Johns Wort

The Rev is your'e man with first hand experience but this is from a medical site.

Possible risks

St John's wort sometimes reacts with other drugs.

You should not take it if you are taking warfarin, cyclosporin, oral contraceptives, anticonvulsants, digoxin, theophylline, or certain anti-HIV drugs. This is because it may reduce the effect of these drugs.

You should not take it at the same time as taking an SSRI antidepressant (selective serotonin reuptake inhibitor) or a triptan drugs used for migraine (such as sumatriptan). This is because it has an additive effect to these drugs which can cause problems.

Because of the uncertain effectiveness, possible side-effects, and possible interactions with other drugs, many doctors now do not recommend that St John's wort should be used. Also, if you have moderate or severe depression, it is generally best that you see a doctor who can advise on treatments and monitor your progress.
 
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